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What Causes Fibromyalgia?

fibromyalgia treatment flagstaff az - Revitalize Ketamine Clinic

What Causes Fibromyalgia?

Fibromyalgia is a chronic pain disorder that affects millions of people worldwide. The condition is characterized by widespread pain, fatigue, and tenderness in the muscles and joints. Although fibromyalgia is a common condition, its causes are not fully understood. In this blog, we will explore some of the possible causes of fibromyalgia and discuss the usefulness of treating fibromyalgia with ketamine.

Central Sensitization

One of the leading theories about the causes of fibromyalgia is that it is a disorder of central sensitization. This means that the brain and spinal cord become more sensitive to pain signals, resulting in increased pain perception. This can be caused by a variety of factors, such as injury, infection, emotional stress, or chronic pain.

It is believed that this heightened sensitivity leads to the brain perceiving pain from stimuli that would not normally be painful, leading to chronic pain and tenderness. Additionally, the brain becomes less responsive to pain-relieving chemicals, making it harder to manage pain with traditional therapies. Understanding the underlying causes of central sensitization is crucial in developing effective treatment options for fibromyalgia.


Another possible cause of fibromyalgia is genetics. Studies have shown that fibromyalgia tends to run in families, suggesting a genetic component to the condition. Research is ongoing to understand the specific genes involved and how they contribute to fibromyalgia. However, it is important to note that genetics is not the only cause of fibromyalgia; other factors such as trauma, infection, and emotional stress may also play a role.


Abnormalities in neurotransmitters, the chemicals that transmit signals in the brain, have also been linked to fibromyalgia. For example, studies have shown that individuals with fibromyalgia tend to have lower levels of serotonin and norepinephrine, which are chemicals that play a role in pain perception and mood regulation. These neurotransmitters are responsible for regulating the pain signals that are sent to the brain, and their deficiency can lead to increased pain perception and sensitivity.

These neurotransmitters also play a role in mood regulation, and their deficiency can lead to depression and anxiety. Therefore, it’s important to note that neurotransmitter imbalances may contribute to the development of fibromyalgia and its symptoms.


Certain infections have been linked to the development of fibromyalgia. For example, some studies have suggested that individuals who have had Lyme disease or Epstein-Barr virus may be more likely to develop fibromyalgia.

Treating Fibromyalgia with Ketamine

Fibromyalgia can be difficult to treat, but ketamine infusion therapy has shown promise in treating the chronic pain associated with fibromyalgia. Ketamine blocks NMDA receptors in the brain, reducing pain, depression, and anxiety. It has also been shown to increase the levels of neurotransmitters such as glutamate and GABA, which can help to regulate pain perception. This is why ketamine infusion therapy can be an effective treatment for fibromyalgia.

At Revitalize Ketamine Clinic, we specialize in ketamine infusion therapy to treat fibromyalgia and other chronic pain conditions. Our team of experts will work with you to create a customized treatment plan that meets your specific needs and goals.

If you’re looking for an effective treatment option for fibromyalgia, contact Revitalize Ketamine Clinic today and schedule your appointment. Let us help you find relief from the pain and discomfort of fibromyalgia and improve your quality of life.

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